A Model for Gene Therapy

This research paper was written in

1978 by Ward Merkeley, M.D. when

he was a first year medical student

attending the University Of Utah

School of Medicine. It is one of the

first original papers suggesting and

exploring the theoretical potentials

and practical limitations of Gene

Therapy. The paper discusses in

technical detail the means of isolating

and inserting a normal hemogloblin

gene into the erythoid stem cells of

people with Sickle Cell Anemia and B

Thalassemia. The difficulties and

limitation of Gene Therapy are

discussed in detail, as well as, some

ethical considerations.