G-CSF in Acute Myocardial Infarction--Experimental and Clinical Findings/Akut Miyokard Infarktusunde G-Csf--Deneysel Ve Klinik Bulgular‪.‬

ABSTRACT Early data from clinical studies suggest that intracoronary injection of autologous progenitor cells may beneficially affect postinfarction remodeling and perfusion. Beyond intracoronary infusion of autologous bone marrow mononuclear CD34+ cells (MNCCD34+), mobilization of stem cells by G-CSF has recently attracted attention because of various advantages such as the noninvasive nature of MNCCD34+ mobilization by subcutaneous injections. It is the aim of the present work to give an overview about the current experimental and clinical findings of G-CSF treatment in acute myocardial infarction. (Anadolu Kardiyol Derg 2006, 6: 261-3)