Revenge is a blade that cuts both ways. Sean MacLeod loses his family to renegades, but in his quest for retribution, he nearly loses his soul. Searching for redemption, he follows the Spirit Trail down the Missouri River, leaving the Blackfoot nation of the north behind for the rugged frontier of the Ozark Mountains. Sean's plans to rebuild his life take an unexpected turn, however, when a local girl is taken hostage by the Osage. Haunted by the ghosts of his past, his choice is a painful one-turn away and do nothing, or get involved and risk losing everything once more.