Early Antibiotic Treatment in a Child with Pandas: A Case Report/Pandas Tanili Bir Cocukta Erken Antibiyotik Tedavisi Bir Olgu Sunumu (Case Report/Olgu Sunumu) (Case Study)
Archives of Neuropsychiatry 2010, June
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Publisher Description
Introduction The spectrum of PANDAS is characterized by a sudden onset of motor tics and obsessive-compulsive disease (OCD) following a group A-beta hemolytic streptococcal (GABHS) infection. OCD is defined as recurrent compulsions or obsessions accompanied by marked distress, consuming more than one hour per day, or interference with daily functions. The PANDAS clinical course was characterized by a relapsing-remitting symptom pattern with significant psychiatric comorbidity accompanying the exacerbations; emotional liability, separation anxiety, nighttime fears and bedtime rituals, cognitive deficits, oppositional behaviors, and motoric hyperactivity were particularly common (1-4). Especially different obsessive-compulsive symptoms can be caused by GABHS infection in children and adolescents (5). The treatment of PANDAS is still unclear according to some research studies (6-8). We assessed short-term antibiotic and antidepressant treatment in this case of PANDAS.