Gestational Prediabetes: A New Term for Early Prevention?(Report)
Indian Journal of Medical Research 2010, Sept, 132, 3
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Publisher Description
Prediabetes The concept of prediabetes refers to blood glucose levels above normal, but not high enough to meet the diagnostic criteria for type 2 diabetes mellitus (DM), traditionally designated as "impaired glucose tolerance" (IGT) and "impaired fasting glucose" (IFG) (1). About 6 to 10 per cent of patients with IGT go on to develop DM annually, and among those with both IGT and IFG, 60 per cent will have DM within six years (2). Thirteen-year trajectories of blood glucose, insulin sensitivity and insulin secretion show that those who develop type 2 DM not only have higher fasting and postload levels of glucose, but higher insulin secretion and lower insulin sensitivity as well (3). The American Diabetes Association recently declared that prediabetes, "IFG and IGT should not be viewed as clinical entities in their own right but rather risk factors for diabetes as well as cardiovascular disease" (4).