The Role of Obesity in Cancer

Research Paper from the year 2014 in the subject Biology - Human Biology, grade: A, The Catholic University of America (Department of Biology), course: Biotechnology, language: English, abstract: Obesity is a known cause of cancer, with worldwide research and epidemiological studies supporting the relationship between obesity and cancer. Obesity can lead to a number of cancers, through cellular and metabolic changes in the body. Hyperinsulenimia, low levels of estrogens and Insulin like growth factor binding protein-3 (IGF-BP3) are among the major causes of cancers that result from obesity. In this study we aim at reviewing the metabolic changes that accompany obesity and cancer, the molecular mechanisms associated with obesity and cancer and finally the epidemiological significance of this relationship.