The Secret of Life: Rosalind Franklin, James Watson, Francis Crick, and the Discovery of DNA's Double Helix
-
- $24.99
Publisher Description
An NPR Best Book of the Year
An authoritative history of the race to unravel DNA’s structure, by one of our most prominent medical historians.
James Watson and Francis Crick’s 1953 discovery of the double helix structure of DNA is the foundation of virtually every advance in our modern understanding of genetics and molecular biology. But how did Watson and Crick do it—and why were they the ones who succeeded?
In truth, the discovery of DNA’s structure is the story of five towering minds in pursuit of the advancement of science, and for almost all of them, the prospect of fame and immortality: Watson, Crick, Rosalind Franklin, Maurice Wilkins, and Linus Pauling. Each was fascinating and brilliant, with strong personalities that often clashed. Howard Markel skillfully re-creates the intense intellectual journey, and fraught personal relationships, that ultimately led to a spectacular breakthrough. But it is Rosalind Franklin—fiercely determined, relentless, and an outsider at Cambridge and the University of London in the 1950s, as the lone Jewish woman among young male scientists—who becomes a focal point for Markel.
The Secret of Life is a story of genius and perseverance, but also a saga of cronyism, misogyny, anti-Semitism, and misconduct. Drawing on voluminous archival research, including interviews with James Watson and with Franklin’s sister, Jenifer Glynn, Markel provides a fascinating look at how science is done, how reputations are undone, and how history is written, and revised.
A vibrant evocation of Cambridge in the 1950s, Markel also provides colorful depictions of Watson and Crick—their competitiveness, idiosyncrasies, and youthful immaturity—and compelling portraits of Wilkins, Pauling, and most cogently, Rosalind Franklin. The Secret of Life is a lively and sweeping narrative of this landmark discovery, one that finally gives the woman at the center of this drama her due.
PUBLISHERS WEEKLY
One of the greatest scientific discoveries of the 20th century was also the scientific heist of the century, according to this action-packed history. Historian Markel (The Kelloggs) recreates the 1953 elucidation of DNA's structure by Cambridge University's James Watson and Francis Crick and their rivalry with the King's College team of Rosalind Franklin and Maurice Wilkins. While for decades history books have attributed the discovery to Watson and Crick, it really wasn't so simple, Markel writes—their discovery was based on Franklin's research that was "borrowed" by Watson. Markel skillfully explains the knotty science behind the breakthrough and highlights the clash of outsize personalities: the mercurial, loudmouthed physicist Crick; the nerdy, manipulative molecular biologist Watson; the prickly X-ray crystallographer Franklin; the "high-strung, bumbling" biophysicist Wilkins; and the world-renowned chemist Linus Pauling (who threatened to beat them all). Markel decries Watson and Crick's secret appropriation of Franklin's X-ray data as "one of the most egregious rip-offs in scientific history" and the culmination of her "oppression" by "white, entitled, English academic lords." His tone sometimes feels overblown, but his tart, sharp-eyed prose—"Chargaff was unimpressed by Crick's nonstop blathering, not to mention Watson's Greek chorus of eye-bulging and snorting"—saves the day. This wonderfully evocative tale sings. Photos.
