Spice and Wolf, Vol. 5 (light novel‪)‬

Arriving in the town of Lenos, Lawrence and Holo take a respite from
their travels north - but a true businessman never rests! It isn't long
before an opportunity for profit presents itself to Lawrence, one that
could fulfill his dreams of owning his own establishment. But as always,
the promise of great reward carries great risk - and risk is never
greater than when one plans to use a wisewolf as collateral! As Lawrence
and Holo feel the ties binding them stretched thin, has the time come
for the pair to go their separate ways?