Potential Application of ELAVL4 Real-Time Quantitative Reverse Transcription-Pcr for Detection of Disseminated Neuroblastoma Cells (Cancer Diagnostics) Potential Application of ELAVL4 Real-Time Quantitative Reverse Transcription-Pcr for Detection of Disseminated Neuroblastoma Cells (Cancer Diagnostics)

Potential Application of ELAVL4 Real-Time Quantitative Reverse Transcription-Pcr for Detection of Disseminated Neuroblastoma Cells (Cancer Diagnostics‪)‬

Clinical Chemistry 2006, March, 52, 3

Clinical Chemistry
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    • 2,99 €

Beschreibung des Verlags

Neuroblastoma (NB), [6] the most common extracranial malignant solid tumor in children, originates from sympathetic nervous tissue in the neural crest. The clinical behavior of NB ranges from a localized tumor with a good prognosis to disseminated disease with unfavorable outcome. Many clinical and biological factors have been shown to affect the prognosis of NB patients (1). Evaluation of bone marrow (BM) metastasis is crucial for correct clinical staging and risk assessment at diagnosis. Detection of residual NB cells in BM is also important for monitoring therapeutic response during treatment. In addition, screening of autologous stem cell preparations is crucial because reinfusion of contaminated stem cell products could lead to systemic recurrence (2-4).

GENRE
Wissenschaft und Natur
ERSCHIENEN
2006
1. März
SPRACHE
EN
Englisch
UMFANG
27
Seiten
VERLAG
American Association for Clinical Chemistry, Inc.
ANBIETERINFO
The Gale Group, Inc., a Delaware corporation and an affiliate of Cengage Learning, Inc.
GRÖSSE
232,4
 kB

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