Remarks on the Foundations of Biology‪.‬

1. INTRODUCTION To say Biology is in "crisis" is, paradoxically, a complement. It is to state that the discipline has progressed to the point where contradictions between its putative founding principles, actual practices, and results are apparent enough to suggest salutary root-and-branch reform. This paper will issue such categorical prescription in the area of Genomics. Much of the rest of what follows is simply reflecting best practice in various subfields of biology.