Efficacy of Chrome Processed Aortic Allograft for Cervical Oesophagoplasty in Dogs (Clinical Report‪)‬

Experimental cervical oesophagoplasty with chrome processed aortic allograft was performed in 12 dogs under general anaesthesia using triflupromazine hydrochloride and thiopentone sodium combination. Hyper alimentation intravenously and through pharyngostomy tube was employed postoperatively in 6 animals each. Morphological, histological and biomechanical studies were performed to assess the healing process. Proliferative changes in the vicinity of the graft material and the perioesophageal tissue were minimum. The grafted site showed satisfactory breaking strength, extensibility, energy absorption and total dilatation capacity on 60th postoperative day. The healing at the site was first intention healing characterized by early infiltration of polymorphs and macrophages followed by vascularisation and fibroplasia. Epithelialization was almost complete by 30th day, but by 60th day, epithelial lining was slightly hyperplasic and lamina propria was devoid of oesophageal glands. Presence of pharyngostomy tube did not influence the healing process. INTRODUCTION