B.P.R.D.: The Black Goddess #4

Outside Memnan Saa's sanctum, two armies of monsters clash over the fate of
the world; within, the B.P.R.D. can only watch as Saa's machinations continue
to unfold around them, building up to an apocalyptic climax with Liz at its
core.

Written by Mike Mignola and John Arcudi, and drawn by Guy Davis, B.P.R.D.:
The Black Goddess is the second of three arcs pulling together threads from
the beginning of the series—leaving the B.P.R.D. and the world forever
changed.