Effect of Apigenin on the Reproductive System in Male Mice (Report‪)‬

1. INTRODUCTION In the early 1970s, several studies in the United States first suggested a possible decline in human sperm concentration [1]. Since then, there has been increased awareness of the possible effects of chemicals on male fertility [2,3]. It is of paramount importance to assess potential health risks associated with exposure to chemical or physical agents since these agents may interfere with the ability of individuals to produce normal progeny. Apigenin is a common flavone present in diet: it is not only in aromatic plants (camomilla, rosemary and parsley), but also in celery, apple, honey, fennel and wheat germ [4-6].