Fibromyalgia: Knowns, Unknowns, And Current Treatment (Disease/Disorder Overview‪)‬

Fibromyalgia is a syndrome characterized by chronic, widespread pain in combination with tenderness to palpation at specific tender point sites on the body, in the absence of otherwise apparent organic disease. It is often associated with other symptoms, such as persistent fatigue, headaches, cognitive or memory impairment, mood disorders, joint stiffness. and insomnia. (1,2) Despite the high prevalence of fibromyalgia (approximately 2% of the population and 3.4% of females in the United States) as well as the increasing public awareness and physician acceptance of the syndrome, understanding its pathophysiology and finding effective treatments continues to be a complex endeavor. (3,4) 2010: What Do We Know?