Timing of NSAID Treatment After Muscle Injury Or Training (More About ... Sports Science) (Non-Steroidal Anti-Inflammatory Drugs ) (Report‪)‬

Injury of skeletal muscle, either severe accidental injury or microdamage as a result of exercise training, is an inevitable outcome of participation in sport, as is the inflammation that follows. Non-steroidal anti-inflammatory drugs (NSAIDs) are probably the most widely used anti-inflammatory treatment. However, many studies have failed to show a benefit of NSAID treatment on actual muscle healing, while some even suggested that it may prolong the recovery period, although it effectively reduces pain and swelling. These conclusions may have been reached due to the fact that NSAIDs treatment is often administered at the wrong time after injury. In order to elucidate this issue, it is necessary to understand the time course of inflammatory events after injury, and the mechanism by which the immune system mediates inflammation.