Lead-Seeking Approaches

Christopher A. Lipinski: Overview of Hit to Lead: The Medicinal Chemist’s Role from HTS Retest to Lead Optimization Hand Off



Jeff W. Paslay • John E. Morin • Richard K. Harrison: High Throughput Screening in the Twenty - First Century


Jack Andrew Bikker • Lakshmi S.Narasimhan: Lead Discovery Using Virtual Screening


Maurizio Pellecchia: NMR Spectroscopy in Fragment Based Drug Design


Kevin D. Freeman-Cook • Daniel W. Kung: Hit Triage – Medicinal Chemistry Strategies to Improve the Odds of Success in Discovery


John W. Ellingboe • Adam M. Gilbert: Lead Identification