Regenerative Medicine for Degenerative Muscle Diseases

This book compiles and
explores cutting-edge research in degenerative skeletal disorders, such as
Duchenne muscular dystrophy and congenital myopathy, and new stem-cell based
therapies and gene replacement therapy. Twelve expertly-authored chapters navigate
the nuances of these treatments in an array of contexts and biological systems.
The topics covered include: How are urine cells from a patient with Duchenne
muscular dystrophy transformed into beating heart cells? What can reprogrammed
cells tell us about heart muscle failure? What do gene mutations mean for those
born with a muscle disease? How are manufacturing methods applied to human stem
cells? Does therapeutic exercise benefit those patients who receive engineered
limb muscle? Is there practical advice about nutrition to enhance muscle
function for the Duchenne patient? Can microRNAs be useful to regenerate
diseased muscle?

 Regenerative
Medicine for Degenerative Muscle Diseases is ideal for scientists
and clinicians from varying disciplines in genetics, cell biology, virology,
cell-based manufacturing, rehabilitation medicine, nutrition, veterinary
medicine and neurosurgery. The reader will see how transformative changes occur
in medicine that can powerfully impact the future for patients suffering from
inherited disorders affecting muscles of the body, including the heart.