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Apolipoprotein A5 and Hypertriglyceridemia (Editorials)
Clinical Chemistry, 2005, Feb, 51, 2
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Publisher Description
Hypertriglyceridemia is associated with increased risk of coronary heart disease (CHD) (1-5), and it is an integral component of the overlapping syndromes of familial combined hyperlipidemia, insulin resistance syndrome, atherogenic lipoprotein profile, and hyperapobetali-poproteinemia (6). More than one mechanism may be involved in the increased risk of CHD associated with increased serum triglycerides: * Triglyceride-rich lipoproteins (TGRLs) may participate directly in atherogenesis, particularly when they have undergone attack by oxygen free radicals (7).
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