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INTRODUCTION Cadmium is a heavy metal of wide occupational and environmental contamination and present in trace levels in seawater and in a broad range of animal and plant species. Relatively large quantities of cadmium are found in commercial phosphate fertilizer, thus the increases in soil and plant cadmium contents may lead to increases in dietary cadmium. Also, cadmium poses a potential environmental hazard due to increased in its industrial use [1-4]. Recently, the effect of long-term exposure to cadmium compounds has been widely investigated [5-9].