Hepatoprotective Activity of Abutilon Indicum on Experimental Liver Damage in Rats‪.‬

Abstract The aqueous extract of Abutilon indicum was tested for hepatoprotective activity against carbon tetrachloride- and paracetamol-induced hepatotoxicities in rats. A. indicum exhibited significant hepatoprotective activity by reducing carbon tetrachloride- and paracetamol-induced change in bio-chemical parameters that was evident by enzymatic examination. The plant extract may interfere with free-radical formation, which may conclude in hepatoprotective action. Acute toxicity studies revealed that the L[D.sub.50] value is more than the dose of 4 g/kg body wt.