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INTRODUCTION Tobacco is one of the most preventable causes of oral cancer. Although there is evidence that smoking (cigarette, cigar and pipe) is associated with oral cancer, the smokeless tobacco (often called chewing tobacco or spit tobacco) seems to be strongly associated with oral cancer (Haumschild and Haumschild, 2009). These findings are based primarily on the epidemiological association of tobacco use with increased incidence of oral cancer. Alcohol and diet have also been reported to be associated with oral Cancer. Kamangar et al. (2009) have reported that 75% of all oral cancers could be attributed to heavy alcohol and tobacco consumption.