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The volume includes a collection of peer-reviewed contributions from among those presented at the main conference organized yearly by the Mexican Statistical Association (AME) and every two years by a Latin-American Confederation of Statistical Societies. For the 2018 edition, particular attention was placed on the analysis of highly complex or large data sets, which have come to be known as “big data”. Statistical research in Latin America is prolific and research networks span within and outside the region. The goal of this volume is to provide access to selected works from Latin-American collaborators and their research networks to a wider audience. New methodological advances, motivated in part by the challenges of a data-driven world and the Latin American context, will be of interest to academics and practitioners around the world.