Stem Cells

During the last two decades, stem cells have progressed from merely a concept to a vibrant field of regenerative medicine which is aimed at addressing the root cause of the problem rather than conventional methods of intervention that mostly provide symptomatic relief.

Stem cell therapy either alone or in combination with the other established treatment strategies is a hope for patients who suffer from the 'incurable' diseases such as Alzheimer, diabetes, myocardial infarction etc. Besides aspirations in the clinical perspective, stem cells provide excellent in vitro disease models for drug development.

Given the significance of the field, the proposed book will be a compilation of the bench experience of experts from various research labs involved in the cutting edge area of stem cell research.
Contents: About the EditorPrefacePluripotent Stem Cell-Derived Cardiomyocytes: Current Research Progress and Therapeutic Potential (Adam T Lynch, Stefan Hoppler)Challenges in Stem Cell-Based Approaches for Myocardial Regeneration after Myocardial Infarction (Violetta A Maltabe, Theofilos M Kolettis, Panos Kouklis)Non-Destructive Metabolomics Characterization of Mesenchymal Stem Cell Differentiation (Amal Ibrahim Surrati, Khawaja Husnain Haider, Virginie Sottile)Cell Therapy for Critical Limb Ischemia: Current Progress and Future Prospects (Pavel Orekhov, Mikhail Konoplyannikov, Vladimir Baklaushev, Peter Timashev, Anatoly Konoplyannikov)Stem Cell-Derived Paracrine Factors Modulate Cardiac Repair (Sadia Mohsin, Mohsin Khan)Cancer Stem Cells and Their Microenvironment (Valentina Masciale, Giulia Grisendi, Federico Banchelli, Roberto D'Amico, Uliano Morandi, Massimo Dominici, Khawaja Husnain Haider, Beatrice Aramini)Mesenchymal Stem Cells for the Treatment of Immune-Mediated Diseases (Ling Ling Liau, Qi Hao Looi, Sue Ping Eng, Muhammad Dain Yazid, Nadiah Sulaiman, Mohd Fauzi Mh Busra, Min Hwei Ng, Jia Xian Law)Chimeric Antigen Receptor (CAR) T-cells as a Therapeutic Modality (Mehmet Özen, Mehmet Gündüz, Khawaja Husnain Haider)Harnessing Stem Cell Secretome Towards Cell-free Therapeutic Strategies (Sharida Fakurazi, Hasfar Amynurliyana A Ghofar, Norshariza Nordin, Suleiman Alhaji Muhammad)Index
Readership: Graduate and Undergraduate Students and Researchers involved in stem cell and gene therapy, cellular and molecular pharmacology, regenerative medicine, cell-based therapy and cell-free therapy. medical graduates, medical doctors and physicians, researchers in the field of cell therapy and cell-free therapy, regenerative medicine, cellular pharmacology, pharmaceutical industry, drug development labs and industries using stem cells as ex-vivo disease models for drug development etc. Members of the educated public may be interested too.Cell Therapy;Cell-Free Therapy;Metabolomics;Paracrine;Regenerative;Stem Cells;Transplantation0Key Features:Covers a broad scope of stem cell research, from their use as drugs to their use as important tools in drug developmentThe contributing authors constitute a blend of established, senior and talented young researchers from some of the top stem cell research labs around the globe