Saran, along with her 'not dead, just no longer human' soul-bond—Tamara, and their giant blue bull leave in search of a handler so Blue can escape Earth and travel outbound. The man Saran meets and falls in love with turns out to be Tamara's husband. Their spiritual joining of three sets into play a prophecy written long ago. Together, they become Tamsarandem, the most powerful soul-bond in all the multiverses.
The shamans pay for their voyage to Terranue, an unknown planet, never before colonized by humans. In return, Tamsarandem must look after the other colonists and help them to prosper and find their Paths of Light. They will need to do this mostly on their own, for the Gods are running out of authorized interventions. However, the God Pane, with the help of the sentient ship-computer, Marybell, constantly search for clever workarounds to ensure The Path of Light will reign supreme upon the final collapse. But there is only so much they can do within their bureaucratic rules.
Having failed to stop Tamsarandem from leaving Earth, those who walk the Path of Darkness embed their own people, including their darkest lord, on the ship to ensure it will never arrive at Terranue.