Antiretroviral Therapy in Adults: January 2008 (GUIDELINES‪)‬

Southern African HIV Clinicians Society These guidelines are intended as an update to those published in the Southern African Journal of HIV Medicine of March 2005 (issue 18, pp.18 - 31). Since the previous guidelines, the scale-up of antiretroviral therapy (ART) in the region has expanded considerably. Cohort studies from the region show excellent clinical outcomes, but ART is still being started in advanced disease and early death rates remain high. New data have become available on antiretroviral (ARV) tolerability in the region and several new ARV drugs have become available. Important new sections have been added on ART use in special populations, including pregnancy and hepatitis B co-infection.