In Vitro Immunomodulatory Activity of Plants Used by the Tacana Ethnic Group in Bolivia. In Vitro Immunomodulatory Activity of Plants Used by the Tacana Ethnic Group in Bolivia.

In Vitro Immunomodulatory Activity of Plants Used by the Tacana Ethnic Group in Bolivia‪.‬

Phytomedicine: International Journal of Phytotherapy & Phytopharmacology 2004, Sept, 11, 6

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Publisher Description

Abstract One hundred and seventy-eight ethanolic plant extracts from the pharmacopoeia of the Tacana, an ethnic group from Bolivia, were screened for immunomodulatory activity using complement cascade inhibition and ADP-induced platelet aggregation inhibition assays. Six impaired both complement pathways (classical and alternative): stem bark from Astronium urundeuvea (Anacardiaceae). Cochlospermum vitifolium (Cochlospermaceae), Terminalia amazonica (Combretaceae). Triplaris americana (Polygonaceae), Uncaria tomentosa (Rubiaceae) and Euterpe precatoria (Arecaceae) roots. Inhibition of complement cascade was independent of essential ion complexation, and was not due to direct hemolytic activity on target red blood cells. For A. urundeuvea, C. vitifolium, and T. amazonica, anti-inflammatory activity relied on cyclo-oxygenase inhibition. Four of these species (A. urundeuva, T. americana, U. tomentosa and E. precatoria) are used traditionally to treat inflammatory processes.

GENRE
Science & Nature
RELEASED
2004
1 September
LANGUAGE
EN
English
LENGTH
18
Pages
PUBLISHER
Urban & Fischer Verlag
SIZE
202.2
KB

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