Tumors of the Central Nervous System, Volume 7

This seventh volume of the essential series covering practices and developments relating to CNS tumors zeroes in on those found in the brain. Detailed dossiers on meningioma and schwannoma tumors cover aspects including diagnosis, therapy and prognosis. The text delivers vital insights into the molecular pathways related to brain tumor biology, including a detailed analysis of the roles played in neoplasm formation by E-cadherin gene instability, carbonic anhydrase 11, urokinase plasminogen activator, and Wnt signaling. Further research into their influence in the process could prompt the development of effective anti-cancer drugs.

The contributions also show how perfusion magnetic resonance imaging helps physicians differentiate between subtypes of meningiomas, and analyze the influence of molecular genetics and epigenetic mechanisms on schwannoma tumors. Among the diagnostic processes outlined are those for recognizing incidentally discovered meningioma, cystic papillary meningioma, facial nerve schwannoma, vestibular schwannoma, and intermediate nerve schwannoma. This book presents treatments for atypical, oncocytic, intracranial, and cavernous meningiomas, as well as guides to therapeutic methods ranging from neurosurgery and gamma-knife radiosurgery to vestibular schwannoma interventions such as retrosigmoidal craniotomy and immunotherapy. This authoritative volume once again provides invaluable and tightly focused source material for medical professionals committed to placing the latest theories and techniques at the service of those they care for.