Alternative Psychosis (Forced Normalisation) in Epilepsy (Case Study) Alternative Psychosis (Forced Normalisation) in Epilepsy (Case Study)

Alternative Psychosis (Forced Normalisation) in Epilepsy (Case Study‪)‬

South African Journal of Psychiatry 2011, June, 17, 2

South African Journal of Psychiatry
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Publisher Description

Brief episodes of abnormal behaviour have been recorded after dramatic reduction of seizures using anti-epileptic drugs (AEDs). This phenomenon is called alternative psychosis, or forced normalisation when supportive electro-encephalogram (EEG) evidence is available. (1-5) Landolt was the first to report improvement in EEG activity during periods of abnormal behaviour. (6-9) The mechanism of forced normalisation is still not fully understood, although the kindling phenomenon, the phenomenon of long-term potentiation and the channel disorder paradigm have all been proposed as possible explanations. (10,11) Another theory relating to this phenomenon states that epileptiform discharges may mimic electroconvulsive therapy in a focal area and this seizure suppression may lead to psychopathology. (2)

GENRE
Health & Well-Being
RELEASED
2011
1 June
LANGUAGE
EN
English
LENGTH
12
Pages
PUBLISHER
South African Medical Association
SIZE
201.7
KB

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