Bone Marrow Lymphoid Infiltrates

Bone Marrow Lymphoid Infiltrates: Diagnosis and Clinical Impact, describes the art of evaluating bone marrow lymphoid infiltrates in the context of their broad spectrum of normal, reactive and malignant status. Reference to the pathogenesis, clinical presentation and outcome complements the diagnostic parameters in each lymphoid disease entity. Physiological lymphoid development, microenvironmental factors and aging changes are unfolded in relation to their influential role in normal and pathological lymphoid conditions. The basic principles and gold standards that should govern a biopsy sample are given in detail, while the establishment of modern techniques is described in terms of their applicability, drawbacks and perspectives.

The 15 chapters that make up this book are the end product of the collaboration amongst European and American experts in different fields, each recognized in their own right for their contribution to bone marrow pathology, clinical approaches and management of lymphoid neoplasms as well as extensive knowledge of modern ancillary techniques.