Prognostic Value of TIMI Frame Count in Patients with Metabolic Syndrome/ Metabolik Sendromlu Hastalarda TIMI Kare Sayisinin Prognostik Degeri (Original Article/Ozgun Arastirma) (Thrombolysis in Myocardial Infarction) (Report‪)‬

In 1988, a complex of symptoms involving hyperinsulinemia, impaired glucose tolerance, hypertriglyceridemia, arterial hypertension, and decreased high-density lipoprotein (HDL) cholesterol was defined as the metabolic syndrome (MS) by G. Reaven (1). G. Reaven was the first to demonstrate that this syndrome is in essence insulin-resistant and that it increases the risk of coronary artery disease. In 1989, J. Kaplan added abdominal obesity to this syndrome and called it the "fatal quartet" (2).