Treatise on Poisons

Excerpt: “Some poisons of this kind act chiefly, if not solely, on the heart. The best examples are infusion of tobacco, and upas antiar. Sir B. Brodie observed, that when the infusion of tobacco was injected into any part of the body, it speedily caused great faintness and sinking of the pulse; and on examining the body instantly after death, he found the heart distended and paralyzed, not excitable even by galvanism, and its aortal cavities filled not with black, but with florid blood, while the voluntary muscles were as irritable as after other kinds of death.""