Flannery Rivers is content to let her sister, Harper, carry on the family dynasty - at the Rivers hospital where they both work and on the home front. Now that Harper is settled and soon to be happily married, Flannery can ease back into her life of casual flirtations and find all the excitement she needs in the ER. She's even got her next playmate all lined up, or so she thinks.
Abigail Remy is a city girl who accepts a position at the imperiled country hospital in the hope of finding a stable, safe community for her teenaged trans son. Unfortunately, when she arrives to work, she discovers the current ER chief is less than happy to be replaced by a fresh-out-of-residency newcomer. Add unexpected attraction to the incendiary mix of city and country, fire and ice, tradition and change - and the prescription is combustible.