Slow Burn: Infected picks up the story of Zed, Murphy, and Jerome where Slow Burn: Zero Day ended. All three have all been infected but have not succumbed to the most pernicious symptoms of the virus. They're not the mindless cannibals that most infected are. Nevertheless, their band of survivors, fearful about the trio's infections, have ostracized them. Now, back on the street, with weapons to defend themselves but little food in their packs, they embark on a search for Murphy's family while following the rumor of a safe haven in the form of a doomsday bunker under a house in east Austin. But the world is more hazardous than they could have guessed. They expect violence from the voracious infected but they have harsh lessons to learn about the lethality of the uninfected. And without people to support the infrastructure of modern civilization, they find that danger comes in many forms.