Mindy Solomon absolutely has to leave Miami. Florida is bad for her head and her hair. She dreams of a dancing career on Broadway and moves to New York, but after a string of failures and mishaps, she realizes that she needs to rethink her grand plan. Finding herself spending way too much time in the comedy club where her future ex-boyfriend works, she nervously goes up onstage one night. People laugh. Not in the places where Mindy thought they would laugh, but hey, it's a start. Mindy and her best friend, Ursula Duran, a man-magnet-model-slash-actress-slash-deeply troubled woman, soon embark on a wild ride that ricochets from New York's West Side Hotel for Women to the comedy circuit, auditions, photo shoots, film premieres, cable TV specials, Hollywood studios, late-night TV talk shows, and beyond. Surrounded by sleazy agents, sleazier lovers, and Ursula's even sleazier mother, the two find that life writes a few punch lines they weren't expecting... but through it all, they somehow manage to have the last laugh.