A Biography of a Chance Miracle explores the life of Lena, a young girl growing up in the somewhat vapid, bureaucracy-ridden and nationalistic Western Ukrainian city of San Francisco. Lena is a misfit from early childhood due to her unwillingness to scorn everything Russian, her propensity for befriending forlorn creatures, her aversion to the status quo, and her fear of living a stupid and meaningless life. As her friends enter college, Lena sets forth on a mission to defend the abused and downtrodden of San Francisco—be they canine or human—armed with nothing more than an arsenal of humor, stubbornness, chutzpah and no shortage of imagination. Her successes are minimal at best, but in the process of trying to save San Francisco's collective humanity, she may end up saving her own. At first glance a crazy and combative girl, Lena just may be the salvation that the Ukrainians of San Francisco sorely need.