A Molecule Away from Madness
Tales of the Hijacked Brain
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4.4 • 29 Ratings
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- $12.99
Publisher Description
Longlisted for the PEN/E.O. Wilson Literary Science Writing Award
Riveting stories of the brain on the brink, from an acclaimed cognitive neurologist.
Our brains are the most complex machines known to humankind, but they have an Achilles heel: the very molecules that allow us to exist can also sabotage our minds. Here are gripping accounts of unruly molecules and the diseases that form in their wake.
A college student cannot remember if she has eaten breakfast. By dinner, she is strapped to a hospital bed, convinced she is battling zombies. A man planning to propose marriage instead becomes violently enraged, gripped by body spasms so severe that he nearly bites off his own tongue. One after another, poor farmers in South Carolina drop dead from a mysterious epidemic of dementia.
With an intoxicating blend of history and intrigue, Sara Manning Peskin invites readers to play medical detective, tracing each diagnosis from the patient to an ailing nervous system. Along the way, Peskin entertains with tales of the sometimes outlandish, often criticized, and forever devoted scientists who discovered it all.
Peskin never loses sight of the human impact of these conditions. Alzheimer’s Disease is more than the gradual loss of a loved one; it can be a family’s multigenerational curse. The proteins that abound in every cell of our bodies are not simply strings of oxygen, hydrogen, nitrogen, and carbon; they are the building blocks of our personalities and relationships. A Molecule Away from Madness is an unputdownable journey into the deepest mysteries of our brains.
PUBLISHERS WEEKLY
Neurologist Peskin debuts with an impressive account of the search for cures for a number of neurologic diseases including dementia and psychosis. In vivid prose, Peskin brings to life the scientists who have contributed to the current "molecular" understanding of such conditions as memory loss and sudden personality shifts. There's Friedrich Miescher, who isolated DNA in the mid–19th century, and Nancy Wexler, who located the gene that causes Huntington's disease in 1979. Elaborating on recent medical advances, Peskin explains how genetic mutations, autoimmune responses, and vitamin deficiencies have been linked to brain maladies, and describes the intense emotional and physical sufferings of patients and their families: one mother "kept watch over her daughter, hoping one of the always answerless doctors would burst into the room and announce the reason for Lauren's illness." Anecdotes run the gamut from depressing to enlightening, the latter exemplified by the story of how Abraham Lincoln's mood swings were linked to mercury poisoning. The case studies can be heavy, but Peskin finds cause for optimism in modern medicine: "People who would previously have been untreatable—and even undiagnosable—have now become curable. Their minds and lives are saved." There's much to savor in this powerful survey.
Customer Reviews
Nice Read
It’s a nice read the stories are compelling, but there are spots in the book that is dry scientific talk. It’s a good introduction to learning about symptoms of dementia