Automated Liquid-Chromatographic Analyzer Used for Toxicology Screening in a General Hospital: 12 Months' Experience (Drug Monitoring and Toxicology) Automated Liquid-Chromatographic Analyzer Used for Toxicology Screening in a General Hospital: 12 Months' Experience (Drug Monitoring and Toxicology)

Automated Liquid-Chromatographic Analyzer Used for Toxicology Screening in a General Hospital: 12 Months' Experience (Drug Monitoring and Toxicology‪)‬

Clinical Chemistry 1997, March, 43, 3

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وصف الناشر

For toxicological screening during acute drug poisoning, laboratories must implement rapid and specific methods. Many laboratories use broad-spectrum screening to determine unknown agents in a patient's sample. Several studies have shown that toxicological screening frequently identifies unsuspected drugs in patients with drug overdoses [1,2]. In a majority of cases, all that is required to guide therapy is qualitative drug screening. Some authors have developed methods for toxicological screening [3,4] based on thin-layer chromatography (TLC) separation and ultraviolet (UV) spectral detection, respectively. (3) Toxi-Lab (Irvine, CA) has developed a drug-screening procedure based on liquid-liquid extraction, TLC separation, and reagent-spray detection (sulfuric acid, Draggendorf reagent).

النوع
علم وطبيعة
تاريخ النشر
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١ مارس
اللغة
EN
الإنجليزية
عدد الصفحات
١٦
الناشر
American Association for Clinical Chemistry, Inc.
البائع
The Gale Group, Inc., a Delaware corporation and an affiliate of Cengage Learning, Inc.
الحجم
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ك.ب.
Resolving Erroneous Reports in Toxicology and Therapeutic Drug Monitoring Resolving Erroneous Reports in Toxicology and Therapeutic Drug Monitoring
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Therapeutic Drug Monitoring in Special Populations (Tdm Conference) Therapeutic Drug Monitoring in Special Populations (Tdm Conference)
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Safety of St. John's Wort Extract Compared to Synthetic Antidepressants (Review) Safety of St. John's Wort Extract Compared to Synthetic Antidepressants (Review)
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C677T and AI298C Polymorphisms of the Methylenetetrahydrofolate Reductase Gene: Incidence and Effect of Combined Genotypes on Plasma Fasting and Post-Methionine Load Homocysteine in Vascular Disease (Molecular Diagnostics and Genetics) C677T and AI298C Polymorphisms of the Methylenetetrahydrofolate Reductase Gene: Incidence and Effect of Combined Genotypes on Plasma Fasting and Post-Methionine Load Homocysteine in Vascular Disease (Molecular Diagnostics and Genetics)
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Doping in Sport: Misuse, Analytical Tests, And Legal Aspects (Editorial) Doping in Sport: Misuse, Analytical Tests, And Legal Aspects (Editorial)
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Transferrin Saturation and Screening of Genetic Hemochromatosis (Letters) (Letter to the Editor) Transferrin Saturation and Screening of Genetic Hemochromatosis (Letters) (Letter to the Editor)
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Effect of Riboflavin Status on the Homocysteine-Lowering Effect of Folate in Relation to the MTHFR (C677T) Genotype (Nutrition) Effect of Riboflavin Status on the Homocysteine-Lowering Effect of Folate in Relation to the MTHFR (C677T) Genotype (Nutrition)
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