This educational Book provides a current overview of the basic mechanism underlying neurodegenerative disorders: protein aggregation. After completing this eBook, readers should be able to understand that neurodegenerative disorders are caused by accumulation of characteristic proteins in neurons and glial cells, and to distinguish which protein is associated with each major neurodegenerative disease. Finally, potential therapeutic approaches that target protein aggregation are discussed.
The target audience is medical or PhD students. The book includes abundant figures and diagrams, and hyperlinks to supporting information (publications or YouTube videos).
Table of contents:
1 | Introduction
2 | Molecular Basis of Protein Aggregation
3 | Therapeutic implications
4 | Remaining challenges
5 | Further reading