Comparison of Immunogenic Efficacy of Mono- and Polyvalent Rabies Vaccines in Dogs (Report‪)‬

Byline: Uzma Farid Durrani, Muhammad Sarwar Khan, Muhammad Athar Khan, Cathleen Hanlon and Susan Moore Abstract.- Monovalent and polyvalent vaccines are commonly used rabies cell culture vaccines that can vary in their immunogenic efficacy in dogs. In this study, immunogenic efficacy of two monovalent vaccines (Rabisin and Rabisyva-VP13) and a polyvalent vaccine (Hexadog DHP-LR) was compared. Sixteen adult, healthy, non-vaccinated dogs were randomly assigned to 4 groups (A to D). Dogs in groups A, B, and C were inoculated with Rabisin (1 dose S/C), Hexadog DHP-LR (1 dose S/C), and Rabisyva-VP13 (1 dose S/C), respectively, at day 0 and 21. Dogs in group D were maintained as negative controls (non-vaccinated).