When scientific research into curing both hunger and obesity goes terribly wrong, a fast moving plague is unleashed and sweeps across New Jersey.
The state is abandoned by the country and sealed off from the world. The victims have become horrific mutations of their former selves. The inhabitants are left to kill or to die.
A soldier, a scientist, a detective, a mobster, a politician and a prepper, along with a beautiful yet dangerous woman from the Philippines, must come together during the first 48 hours of the outbreak and journey through chaos towards their only chance of escape on the Garden State Parkway–Exit Zero.