Feed Your Genes Right

PUBLISHERS WEEKLY JAN 31, 2005

Offering an unusual mix of hard science, commonsense nutritional advice and even a handful of recipes, this book counsels readers to take control of their bodies (and, more specifically, their genes) by being knowledgeable about what to feed them. "Nutrients provide the building blocks of genes, and they turn many genes on and off," Challem notes. Therefore, what you eat determines not only your energy level and your belt size, but also your risk of DNA damage and disease. Challem, coauthor of Syndrome X, packs his volume with information on specific genetic conditions and advice on how to avoid or ameliorate them, as well as general tips for healthy living. The text is well organized but full of arduous terminology, particularly the latter half, which details specific diseases and their genotypes. At one point, for example, Challem notes that "people with an inefficient APOE E4 variation of the apoliprotein gene, which is relatively common in some parts of Scandinavia, tend to have higher blood-cholesterol levels and are more likely to suffer a heart attack." Though Challem stuffs his book with facts and makes frequent references to clinical studies, readers may be skeptical of some of his claims. (He asserts, for example, that many of the biochemical problems associated with Down Syndrome "can be circumvented through high-dose vitamin and mineral supplements and thyroid medications, leading to improved intelligence and appearance.") Not all readers will embrace Challem's prescriptions, or his sometimes technical writing, but those interested in the science of healthy living, particularly the nuts and bolts of the body's inner-workings, will find this a fascinating read.