Harmattan Rain follows three generations of women as they cope with family, love and life. A few years before Ghana's independence, Lizzie-Achiaa's lover disappears. Intent on finding him, she runs away from home. Akua Afriyie, Lizzie-Achiaa's first daughter, strikes out on her own as a single parent in a country rocked by successive coups. Her daughter, Sugri grows up overprotected. She leaves home for university in New York, where she learns that sometimes one can have too much freedom. In the end, the secrets parents keep from their children eventually catch up with them.