Sixteen-year-old Jolene, named after the girl in the Dolly Parton song, is from a long line of lowlifes, but at least they're musical lowlifes. Her mother is a tanning-salon manager who believes she can channel her karaoke habit into a professional singing career. Jolene's dad, a failed bass player, has gone back to the family demolition business and lives by the company motto: "We do not build things; we only tear them down." But Jolene and her big brother, Matt, are true musicians, writing songs together that make everything Jo hates about their lives matter less.
When Matt up and leaves in the middle of the night, Jo loses her only friend, her support system and the one person who made her feel cool. As it becomes clear that Matt is never coming back, Jo must use music to navigate her loss.