Human Microdosing; A Boon Or a Bane? (Correspondence)
Indian Journal of Medical Research 2009, August, 130, 2
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Publisher Description
Sir, Drug Development is time consuming and complex, requires 10-15 years of sustained efforts, and a cost of 500 million [pounds sterling] to 1 billion [pounds sterling] for a single marketed drug (1). Nearly 40 per cent of the investigational new drugs (INDs) fail in the phase-1 trials owing to the inappropriate pharmacokinetics (PK) of the test compound (2).
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