The 'Medical Education in Cases' Volume 5 is the last and final volume of this popular case series. These case books put difficult medical education cases under a microscope. We post challenging hypothetical dilemmas, moderate discussions on potential approaches, and recruit medical education experts to provide their insights. For further insight and reference, curated comments from the medical community can be found alongside each case. These cases and the commentaries were originally released via the 'Academic Life in Emergency Medicine' website (www.aliem.com/medic), and are still available as single PDF downloads. Our editorial team created this e-book to promote easy access and use of medical education resources for our readers.