PRIMERS FOR PROTEOMICS

This book contains examples written by internationally recognized experts applying proteomics and analysis applications of mass spectrometry in their everyday research. They dedicate this book to a broad audience of all scientists to encourage them to use the omics approach to investigate biological processes.

The first chapter is a short introduction to the basics of analytical chemistry. The following chapters describe high-throughput proteomic studies and how they are applied in various areas of biological and biomedical sciences, providing valuable insights into how biological systems work at the molecular level.

Contents:
Analytical Primer (Katarzyna Pawlak and Pawel Ciborowski)Ionization — The First Step of Mass Spectrometry-Based Proteomic Analysis (Katarzyna Macur)Basic Proteomics Protocols (Paulina Czaplewska and Marc Muller)Improving the Basic Workflow (Paulina Czaplewska, Natalia Musiał, and Michał Puchalski)Amino Acid Sequence Databases and Search Engines — Basic Tools in Proteomic/Peptidomic Research (Aleksandra E Bogucka and Stanisław Ołdziej)Chemometrics in Proteomics (Beata Walczak)Basics of MS-Based Glycomic and Glycoproteomic Analysis of Glycoproteins (Yehia Mechref, Wenjing Peng, Cristian D Gutierrez Reyes, Andrew Bennett, Firas Kobeissy, and Stefania Mondello)Mapping Subcellular Proteomic Landscapes with Mass Spectrometry (Trisha Tucholski, Caleb Bridgwater, and Aleksandra Nita-Lazar)Cardiovascular Proteomics Primer: Managing Expectations and Setting Yourself up for Success (Linda Berg Luecke, Melinda Wojtkiewicz, Claudius Mahr, and Rebekah L Gundry)AmyloidosisMass Spectrometry–Based Immunopeptidomics for the Cancer Vaccine Science (Sachin Kote)Proteomics Approach to Viral Infections (Pawel Ciborowski and Michael Belshan)
Readership: Researchers and graduate students in Mass spectrometry and Proteomics.

Key Features: An easy read for beginners to be introduced to mass spectrometry based proteomics Provides an introduction to basic methodology of high-throughput data analysis and chemometrics Covers an application of proteomics in the study of complex biological systems