Holmes is asked to find Selena when her maid, Mrs. Baker, receives a threatening letter addressed to Miss Jones. When Holmes finds her, he realizes he has set eyes on her before. A criminal league that has been building for some time and is now being hampered by her wits and presence. These men will stop at nothing to prevent her from any further interference. A great evil rains down upon Selena causing a chain of events that will bring Holmes and his dear friend Watson to her side. These events soon lead to a kidnapping and the mastermind behind the entire affair. They find themselves in grave danger as the case takes a turn for the worst and Watson is taken prisoner. A ruse is set for Holmes, and Selena struggles to save Watson and reach Holmes in time. Her last venture, with Holmes, proves to be a deadly one but for whom?