The Use of ACE Inhibitors and Arbs in Severe Chronic Kidney Disease: Point--Counterpoint (Pharmacy News and Reviews) (Angiotensin-Converting Enzyme) (Angiotensin Receptor Blockers) (Clinical Report‪)‬

As health care providers practising evidence-based medicine, we must continually keep current on new literature in our field. Oftentimes, we are left with the daunting task of deciphering the practical implications of seemingly contradictory messages. In particular, there has been much debate regarding the use of inhibitors of the renin-angiotensin-aldosterone system (RAAS), namely angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs) in the severe chronic kidney disease (CKD) patient population. [ILLUSTRATION OMITTED]