Ruth Clarkson-Smythe has vanished! To solve the mystery, Dr. Yakushev needs help from Natalia, Joe and Alejandro, plus his resourceful new girlfriend, an offbeat octogenarian, and the secret visitors in his laboratory.
Despite their efforts, problems arise to thwart them at every turn. Equipped with a new mobile time machine and the assistance of a miraculous substance called Zarulium, Yakushev and his team inadvertently explore the self-consistency and parallel universe theories, trying not to wipe out their own lives in the process.
While Natalia, Joe and Alejandro work hard at developing their mutations and Mantis, the former assassin, attempts to start over, Anton's lab-dwelling guests receive an unexpected message from home.