Effect of Intrauterine Transfusion on Neonatal Outcomes in Rh Hemolytic Disease/Rh Hemolitik Hastaliginda Intrauterin Transfuzyonun Neonatal Sonuclara Etkisi (Original Article/Ozgun Arastirma) (Report) Effect of Intrauterine Transfusion on Neonatal Outcomes in Rh Hemolytic Disease/Rh Hemolitik Hastaliginda Intrauterin Transfuzyonun Neonatal Sonuclara Etkisi (Original Article/Ozgun Arastirma) (Report)

Effect of Intrauterine Transfusion on Neonatal Outcomes in Rh Hemolytic Disease/Rh Hemolitik Hastaliginda Intrauterin Transfuzyonun Neonatal Sonuclara Etkisi (Original Article/Ozgun Arastirma) (Report‪)‬

The Journal of Current Pediatrics 2010, June

The Journal of Current Pediatrics
    • 5,99 лв.
    • 5,99 лв.

Publisher Description

Giris Fetus ve yenidoganin Rh hemolitik hastaligi, plasentadan gecen maternal ozgul IgG Rh otoantikorlarinin eritrositlere baglanarak progresif fetal hemoliz ile sonuclandigi klinik tablodur. Rh negatif bir anne, fetomaternal hemoraji yolu ile Rh pozitif bebeginin RhD antijenlerine maruz kalmasi sonucu Rh izoimmunizas-yonu gelisimi acisindan risk altinda kalmaktadir (1). Ilk yanit zayif olup, esas olarak plasentayi gecemeyen IgM antikorlari ile olmaktadir. Ikinci kez Rh pozitif eritrositlere maruz kalinmasi durumunda ise plasentayi gecen IgG antikorlari ile yanit olusmakta ve fetal anemi, hidrops fetalis ve tedavi edilmemesi durumunda intrauterin fetal olum ile sonuclanmaktadir (2,3). Izoimmunizasyon esas olarak ikinci veya daha sonraki Rhpozitif gebeliklerde olusmaktadir. Immun profilaksi uygulanmamasi durumunda Rh-negatif anneden dogan Rhpozitif bir bebekte %16 oraninda Rh izoimmu-nizasyonu gelisim riski mevcuttur (4).

GENRE
Health & Well-Being
RELEASED
2010
1 June
LANGUAGE
EN
English
LENGTH
11
Pages
PUBLISHER
Galenos Yayinevi Tic. Ltd.
SIZE
244.8
KB

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